REACT

Restrictive Eating and Athlete Cognition Trial

A study for 14-30 year old females with restrictive eating and/or athletes who have missed periods in the last 6 months

Study Aim
 

Research has shown that females with eating disorders have lower levels of estrogen, leading to irregular or missed periods. Estrogen is involved in mental flexibility and reward responsiveness. This study aims to investigate whether replacing estrogen levels in young females with restrictive eating and/or athletes who have irregular periods will improve mental flexibility and reward responsiveness. 

The study will be 4 months long and will include 4 visits: a screening visit, a baseline visit, an 8 week visit, and a 12 week visit. 

 

If you are eligible and interested in the study, we will contact you to schedule a screening visit. This visit will help us determine if you are eligible beyond what we can learn from you over the phone. 

Study Visits
 
Total compensation up to $500

Initial Screening Visit

  • History, Physical & Bloodwork

  • Psychological assessment

  • Brief questionnaires

Baseline

8 Week Visit

12 Week Visit

  • History, Physical & Bloodwork

  • Behavioral interview

  • Brief questionnaires

  • Neuroimaging MRI scans

  • Computer tasks

  • Food diary

  • History, Physical & Bloodwork

  • Brief questionnaires

  • Neuroimaging MRI scans 

  • Computer tasks

  • History, Physical & Bloodwork

  • Behavioral interview

  • Brief questionnaires

  • Computer tasks

  • Food diary

Study Coordinators: 

Meghan Lauze

617-643-4034

Click here to email

Amelia Moser

(McLean Hospital)

Nurse Practitioner:
Meghan Slattery
617-643-0267
Click here to email

 

Co-Investigators:
Franziska Plessow, PhD
Jennifer Thomas, PhD
Elizabeth Lawson, MD
Poornima Kumar, PhD (McLean Hospital)
 

 

Principal Investigators:
Kamryn Eddy, PhD
Madhu Misra, MD
Diego Pizzagalli, PhD
(Site PI; McLean Hospital)
 

 

 

ANEreact@mgh.harvard.edu

617-643-0267

 

A few past participants kindly shared their experiences with us, which you can read here: Participant 1 & Participant 2

© 2013 MGH Adolescent Neuroendocrine Unit.

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