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REACT

Restrictive Eating and Athlete Cognition Trial

A study for 14-35 year old females with restrictive eating and/or athletes who have missed periods in the last 6 months

Study Aim
 

Research has shown that females with eating disorders have lower levels of estrogen, leading to irregular or missed periods. Estrogen is involved in mental flexibility and reward responsiveness. This study aims to investigate whether replacing estrogen levels in young females with restrictive eating and/or athletes who have irregular periods will improve mental flexibility and reward responsiveness. 

The study will be 4 months long and will include 4 visits: a screening visit, a baseline visit, an 8 week visit, and a 12 week visit. 

 

A few past participants kindly shared their experiences with us, which you can read here: Participant 1 & Participant 2

Interested in learning more?

 

Click here to read about one coach's new approach to training female athletes.

Click here to listen to a podcast about female Olympians and Paralympians from Harvard Kennedy School's Women and Public Policy Program.

Click the box below to read more about our unit's research.

If you are eligible and interested in the study, we will contact you to schedule a screening visit. This visit will help us determine if you are eligible beyond what we can learn from you over the phone. 

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Study Visits
 
Total compensation up to $525

Initial Screening Visit

Baseline

8 Week Visit

  • History, Physical & Bloodwork

  • Psychological assessment

  • Brief questionnaires

  • History, Physical & Bloodwork

  • Behavioral interview

  • Brief questionnaires

  • Neuroimaging MRI scans

  • Computer tasks

  • Food diary

  • History, Physical & Bloodwork

  • Brief questionnaires

  • Neuroimaging MRI scans 

  • Computer tasks

Study Coordinators:
 

Meghan Lauzé

617-643-4034

Click here to email

Felicia Petterway

617-724-6046

Click here to email

Macy Turley

617-643-7847

Click here to email

Nurse Practitioner:

Meghan Slattery
617-643-0267
Click here to email

Sarah Smith
Click here to email
Co-Investigators:
 
Franziska Plessow, PhD
Jennifer Thomas, PhD
Elizabeth Lawson, MD
Lauren Breithaupt Langston, PhD
Diego Pizzagalli, PhD (McLean Hospital)
 

 

12 Week Visit

Principal Investigators:
Kamryn Eddy, PhD
Madhu Misra, MD MPH
Poornima Kumar, PhD
(Site PI; McLean Hospital)
 

 

  • History, Physical & Bloodwork

  • Behavioral interview

  • Brief questionnaires

  • Computer tasks

  • Food diary