Young Athlete
Determinants of Skeletal Health in Male Athletes
A study for 16-30 year old male athletes who are running
at least 30 miles/week
Study Aim
Research in female athletes has shown that high levels of exercise can cause low energy availability, hormonal irregularities, and impaired bone density. However, similar studies in males have not yet been conducted. In this study, we aim to investigate whether male athletes are also at risk for compromised bone strength due to low energy availability and resultant hormonal irregularities.
This study is 18 months long including a screening visit to assess eligibility, main visits at baseline and 12 months, and check-ins at 4, 8, and 18 months. 
Study Visits
Total Compensation up to $1300
Baseline and 12 Month Visits:



  • History, Physical, and Bloodwork

  • Bone density scan

  • Peripheral CT scan of arm and leg

  • MRI for body composition

  • Metabolic testing

  • Questionnaires about exercise, diet, and eating behaviors/attitudes 

  • Assessments of activity level and heart rate 

4 Month and 8 Month Visits:
May be conducted virtually



  • History and Physical

  • Assessments of diet, activity level, and heart rate

18 Month Phone Call:


  • Evaluation of any bone sports injuries 

Compensation Breakdown:
Baseline: $200
4 Month / 8 Month: $250 each
12 Month: $500
18 Month Phone-Call: $100


Study Coordinators: 

Amita Bose

Bryan Bollinger

Nurse Practitioners: 

Anu Gerweck

Meghan Slattery


Adam Tenforde, MD

Kathryn Ackerman, MD, MPH

Melanie S. Hanes, MD

Principle Investigators: 

Karen K. Miller, MD

Madhusmita Misra, MD, MPH