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Pediatric Endocrine-Neuroendocrine-Sports Endocrine Research

Improving Health Through Research
In Conjunction with the Eating Disorders Clinical and Research Program (EDCRP) at Massachusetts General Hospital
(CLOSED)
Bone Health Study
Effects of Anorexia Nervosa on Peak Bone Mass
A study for 14-22 year old females with Anorexia Nervosa
No Longer Accepting Volunteers

Study Aim
Our goal is to determine whether a combination of estrogen (a hormone that has been proven to prevent bone loss) and insulin-like growth factor-1 (a hormone that increases bone formation) improves bone density in adolescent girls with anorexia nervosa.
This is a 12-month treatment study.
Study Visits
Total Compensation up to $910
Baseline, 6 Month, and 12 Month Visit:
Completed at MGH
$90 compensation for each visit
Visit Length: 3 hours
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History, Physical Exam, and Bloodwork
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Bone Density Scan
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Hormone Evaluation
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Periphera CT Scan (wrist and leg)
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MRI (optional)
1.5, 3, 4.5, 7.5, 9, and 10.5 Month Visits:
Completed offsite or at MGH
$90 compensation for each visit
Visit Length: 30 minutes
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History, Physical, and Bloodwork only
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Many participants choose to complete these visits at their PCP's office, a nearby lab, or their Student Health Center
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